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The Terry Fox Research Institute (TFRI), named for Canadian icon Terry Fox, is built on Terry's dream to end cancer through research.

News & Notices

  • Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery, study finds

    A new study by Dr. Rebecca Auer, a member of TFRI's Oncolytical Virus project and a former recipient of the TFRI New Investigator Award, suggests that a common treatment for erectile dysfunction combined with the flu vaccine may be able to help the immune system mop up cancer cells left behind after surgery. The study, published in OncoImmunology, shows that this unconventional strategy can reduce the spread of cancer by more than 90 percent in a mouse model. It is now being evaluated in a world-first clinical trial.

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  • Breakthrough test uses ctDNA to determine treatment resistance in advanced prostate cancer patients

    Metastatic castration-resistant prostate cancer (mCRPC) patients are now one step closer to more personalized treatment, thanks to a new test that can distinguish who will respond well to standard therapies and who will become resistant to treatment.

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  • Targeting hypoxia can, in turn, target cancer-initiating cells in colorectal tumours

    Targeting hypoxia can, in turn, target cancer-initiating cells (C-ICs) in colorectal cancer a study team in Toronto has found. Additionally, the team has discovered a biomarker for hypoxia to identify tumours that would most benefit from this innovative treatment method.

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  • TFRI-funded researchers uncover “evolutionary arms race” between cancer and immune system

    A new study led by a team of TFRI-funded researchers has uncovered the mechanisms through which deadly ovarian cancer cells escape the immune system, setting the stage for a better understanding of how and why patients respond to promising new immunotherapies.

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Our Cancer Research

Group is changing the cancer imaging landscape with groundbreaking work

Their work on porphysome nanoparticles and photoacoustic imaging has led to a Canadian invention that Dr. Gang Zheng and his team hope will bring new benefits to patients, particularly those with prostate and thyroid cancers, two diseases currently lacking minimally invasive, safe and effective destruction of tumours. Their technology uses light that is absorbed by nanoparticles to destroy tumour tissue without damaging normal tissue. 

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Achieving Terry Fox's Dream Through Cancer Research

Our Mission & Vision

Terry's vision unites us and inspires our research excellence, innovation and creativity. The Terry Fox Research Institute is a collaboratively oriented, pan-Canadian organization focused on improving cancer research outcomes for the benefit of cancer patients everywhere. We invest in and manage translational research projects across Canada and function as the research arm of The Terry Fox Foundation, managing and overseeing its discovery and training portfolios. We want to ensure that today’s best science becomes tomorrow’s affordable medicine.


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